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Derepression
ββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββ
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Contents
β’ Eigenschaften
β’ Weblinks
β’ Einzelnachweise
ββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββ
Eigenschaften
Nicht alle Gene werden zu jederzeit abgelesen. Manche Gene werden nur in bestimmten ZeitrΓ€umen (z. B. bei der Ontogenese) und in einzelnen Zelltypen (z. B. in einzelnen Geweben oder Organen) transkribiert. Durch die Repression wird die Transkription eines Gens verhindert, wΓ€hrend die Derepression den umgekehrten Vorgang bezeichnet.
Die Derepression erfolgt durch Freigabe eines blockierten Gens, z. B. durch Bindung eines Induktors an den Repressor oder durch epigenetische Modifikation.cite-ref-1[1] Der gebundene Induktor fΓΌhrt zu einer Freisetzung des Repressors vom Operator in dem Operon, dessen Transkription blockiert ist. Das dereprimierte Operon kann anschlieΓend durch die Transkription zur Genexpression fΓΌhren. Beispiele fΓΌr die Derepression sind die Regulation der Transkription der Ξ΄-AminolΓ€vulinat-Synthasecite-ref-2[2] oder der Rezeptor des luteinisierenden Hormons.cite-ref-3[3]
Weblinks
β’ Definition of 'Derepression'., the Free Dictionary.com
Einzelnachweise
cite-note-33. β M. L. Dufau, M. Liao, Y. Zhang: Participation of signaling pathways in the derepression of luteinizing hormone receptor transcription. In: Molecular and Cellular Endocrinology. Band 314, Nummer 2, Januar 2010, S. 221β227, ISSN 1872-8057. doi:10.1016/j.mce.2009.05.005. PMID 19464346. PMC 2815110 (freier Volltext).